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COVID-19 is an emerging, rapidly evolving situation. Here, we report a case of a very rare subtype of MBC—a mixed-type metaplastic breast cancer with osseous differentiation. Clipboard, Search History, and several other advanced features are temporarily unavailable. Nielsen and Jakobsen described a breast cancer case in a 32-year-old man . Breast metaplastic carcinomas are aggressive.They have worse prognosis compared to other breast cancers. 2002;40:215–22. -, Kim EK, Lee MK, Oh KK. Breast cancer regression was reported in 43/741 cases of spontaneously regressing cancers compiled and summarized by Challis and Stam in a review of the period from 1900 to 1987 [ 3 ], and few additional reports have been published since then [ 4, 5, 6, 7, 8, 9 ]. The patient received neoadjuvant chemotherapy with adriamycin/cyclophosphamide (AC) followed by docetaxel/trastuzumab. Primary small cell carcinoma of the breast: a case report This case report sheds light on a rarely described disease and provides a comprehensive approach to diagnosis and management. 2020 Mar-Apr;53(2):105-111. doi: 10.1590/0100-3984.2019.0056. Its early recognition and accurate distinction from primary breast cancer are of crucial importance to choo … Menacée d’être reportée à cause de la pluie et du vent engendrés par la tempête Dennis, la rencontre entre Brest et l’ASSE, prévue ce dimanche à 17 heures, est maintenue. Multiple Myeloma involving the breast is very rare and the diagnosis is challenging because the clinical and radiological features of breast multiple myeloma are indistinguishable to other forms of breast disease whether primary or metastatic. Breast cancer is the most common malignant tumor in women that usually arises from the epithelial or stromal components of the breast tissue , whereas primary breast lymphoma (PBL) represents an extremely rare entity that accounts for approximately 0.04–0.5% of all breast malignancies and 0.38–0.7% of all lymphomas.Furthermore, most PBL cases are of B-cell … Phyllodes tumor (PT) of the breast are neoplasms typically presented as painless, lobulated with a size that varies from 2 to 10 cm, they have an incidence of less than 1% of all breast tumors. Case Rep Med. Bethesda, MD 20894, Copyright Locally-advanced primary neuroendocrine carcinoma of the breast: case report and review of the literature. Front Endocrinol (Lausanne). The mammographic and ultrasound findings of osseous metaplasia depend on the cause. -. Prevention and treatment information (HHS). This case report sheds light on a rarely described disease and provides a comprehensive approach to diagnosis and management. A granular cell tumor involving the breast parenchyma was first described by Abrikossoff in 1931. An open biopsy demonstrating lactating adenoma was considered discordant and surgery was performed to confirm the diagnosis. It has been reported that breast cancer that is not inflammatory is associated with dermatomyositis and that treatment of the breast cancer improves the symptoms of dermatomyositis, which is a feature of the paraneoplastic syndrome [ 9 ]. Jain S, Agarwal JP, Gupta T, Parikh PM, Mistry RC, Menon H, Pramesh CS, Shrivastava SK. Partial breast resection for multifocal lower quadrant breast tumour using virtual reality Enora Laas , Mohamed El Beheiry , Jean-Baptiste Masson , Caroline Malhaire BMJ Case Reports CP Mar 2021, 14 (3) e241608; DOI: 10.1136/bcr-2021-241608 The patient had lost 8 kg, but experienced no … -, Zhu Y, Li Q, Gao J, He Z, Sun R, Shen G, et al. The first report was made by Koenig published the first 4 cases in 1998. She had no history of breast cancer in her first-degree relative. 2013 Apr;23(4):282-4. described the case of a 16-year-old male with unilateral ductal carcinoma in situ and gynecomastia . -. 1996;26(11):929-32. doi: 10.1007/BF00311799. Although a granular cell tumor of the breast is a rare breast neoplasm, it should be considered in the differential diagnosis of benign and malignant lesions. eCollection 2018. See this image and copyright information in PMC. A copy of the written consent is available for review by the Editor-in-Chief of this journal. Neuroendocrine breast cancer is a rare entity that was defined in 2003 by the World Health Organization as a separate breast cancer subtype. Validire P, Capovilla M, Asselain B, et al. Clinical … The prognosis of AS is reportedly poor. A histological examination combined with immunohistochemical study revealed it to be a granular cell tumor. We herein report the case of a 47-year-old white woman with a left breast mass that was found to be an early-stage, high-grade small cell carcinoma of the breast. Would you like email updates of new search results? -, Brown AC, Audisio RA, Regitnig P. Granular cell tumour of the breast. It has a very poor prognosis and warrants treatment with platinum-based chemotherapy. Neuroendocrine differentiation and prognosis in breast adenocarcinoma. See this image and copyright information in PMC. The most common sites of mucinous cystadenocarcinoma include the ovary, pancreas, and appendix. 2021 Jan 4;7(1):3. doi: 10.1038/s41523-020-00207-3. Neuroendocrine carcinoma of the breast is a well-defined histologic subtype of breast cancer. Clinically, carcinosarcoma of the breast is an aggressive breast cancer. Honma N, Sakamoto G, Ikenaga M, Kuroiwa K, Younes M, et al. Here we report an unusual … Please enable it to take advantage of the complete set of features! doi: 10.1046/j.1365-2559.2002.01336.x. In a review of 307 cases of breast neoplasms containing bone or cartilage,1/90 fibroadenomas and 2/158 breast carcinomas contained bone, one benign mesenchymoma contained cartilage, and one was a benign “mixed” tumor containing both bone and cartilage. Neuroendocrine breast carcinoma: a rare but challenging entity. Epub 2011 Feb 12. We report the case of a 32-year-old Moroccan woman who presented with a palpable mass in her right breast. Ohnishi H, Nishihara K, Tamae K, Mitsuyama S, Abe R, Toyoshima S, Abe E. Surg Today. López-Bonet E, Alonso-Ruano M, Barraza G, Vazquez-Martin A, Bernadó L, Menendez J. Carcinosarcoma of the breast, often referred to as metaplastic carcinoma of the breast, is a rare malignancy with two distinct cell lines described as a breast carcinoma of ductal type with a sarcoma-like component. Fatnassi R, Bellara I. Primary neuroendocrine carcinoma of the breast. CASE REPORT In 2020, a 32-year-old female who was diagnosed with Hurler syndrome at one year of age presented with a left upper outer quadrant breast mass that she noticed during a shower. Samli B, Celik S, Evrensel T, Orhan B, Tasdelen I. Arch Pathol Lab Med. Introduction: Background Breast angiosarcoma (AS) is a rare malignant breast tumor arising from endothelial cells lining the blood vessels. Mammography and ultrasounds did reveal a lesion in situ. The primary mucinous cystadenocarcinoma of the breast is a very infrequent tumor. However, metastasis to the bladder is uncommon. We report the case of a patient with a breast sarcoma, treated with neoadjuvant chemotherapy and discuss the appropriate pathological evaluation and therapeutic management. In 2008, Chang et al. Breast sarcoma is a rare entity; it is a heterogeneous group of uncommon neoplasms arising from mesenchymal tissues of the breast. Clinically, carcinosarcoma of the breast is an aggressive breast cancer. -, Tan PH, Schnitt SJ, van de Vijver MJ, Ellis IO, Lakhani SR. Papillary and neuroendocrine breast lesions: the WHO stance. Breast Cancer. doi: 10.1155/2014/408459. Carcinosarcoma of the breast, often referred to as metaplastic carcinoma of the breast, is a rare malignancy with two distinct cell lines described as a breast carcinoma of ductal type with a sarcoma-like component. 1999;6(1):55–58. 2015;66:761–70. 1. El Aouni N, Laurent I, Terrier P, Mansouri D, Suciu V, Delaloge S, Vielh P. Granular cell tumor of the breast. Moreover, MM in the breast has been rarely documented [ 2 – 4 ]; the first case of MM in the breast was reported in 1925 [ 4 ]. We report a case of Paget's disease in a 43-year-old woman who presented eczema of the nipple. Breast ultrasound and mammography were performed showing a rounded, hypoechoic solid lesion with ill-defined margins in the right inner-inferior quadrant, suspicious of malignancy. Careers. We report a case of a 25-year-old female presenting with two large, ulcerative and bleeding breast masses. Biomed Res Int. We present this case because of the rarity of this tumor. Primary breast lymphoma was first defined by Wiseman and Liao in 1972. COVID-19 is an emerging, rapidly evolving situation. Oncol Rep. 2008;20:1369–74. Case report: We discuss a case of a 60 year-old woman who began to experience pain in her right breast in January 2009. Privacy, Help Case report A 39-year-old female presented with a lump in her left breast with no other complaint. 2011;2011:972168. Current Breast Cancer Reports provides in-depth review articles contributed by international experts on the most significant developments in the field. Small cell carcinoma of the breast is a rare subtype of neuroendocrine breast cancer. Albasri AM, Ansari IA, Aljohani AR, Alhujaily AS. 2000;41(5):673–675. 2013;19:382–7. Breast cancer frequently metastasizes to the bone, lung, and liver. 2009;84(3):133–139. We report the case of one such patient who developed contralateral breast cancer 40 years after her initial breast cancer diagnosis. The mass had rapidly increased in size over six months. Tachibana K, Abe N, Abe S, Aoto K, Okano M, Murakami F, Kawana S, Suzuki O, Tasaki K, Ohtake T, Takenoshita S. Gan To Kagaku Ryoho. Breast cancer frequently metastasizes to the bone, lung, and liver. Primary breast non-Hodgkin’s lymphoma: a large single center study of initial characteristics, natural history, and prognostic factors. Br J Radiol. The mass was in contact with her latissimus dorsi and suspicious for malignancy. Keywords: National Library of Medicine Breast J. Am J Hematol. At the time, she denied breast pain, … Granular cell tumour of the breast: MRI findings and review of the literature. Case Rep Surg. In this article the authors report a case presented with breast masses, which were found to be extra osseous Multiple Myeloma. Prevention and treatment information (HHS). Validire P, Capovilla M, Asselain B, et al. Angarita FA, Rodríguez JL, Meek E, Sánchez JO, Tawil M, Torregrosa L. World J Surg Oncol. FOIA The treatment and prognosis of neuroendocrine breast cancer are still not well established. 2009;84(3):133–139. The morphological features of AME that might predict malignant potential have not been elucidated. TTF-1 Positive Primary Small Cell Carcinoma of the Breast: A Case Report and Review of the Literature. We present the case of a 75-year-old woman with a history of a benign fusocellular tumor of the right breast diagnosed with a borderline phyllodes tumor and then presenting degeneration to a … Primary breast non-Hodgkin’s lymphoma: a large single center study of initial characteristics, natural history, and prognostic factors. 2008 Apr;81(964):e120-2. 1. Expression of neuroendocrine markers in different molecular subtypes of breast carcinoma. Would you like email updates of new search results? 2011 Jun;63(2):139-42. doi: 10.1007/s13304-011-0051-1. Case presentation. No need for approval from our ethics committee. Diagn Cytopathol. (2003) Mucinous cystadenocarcinoma of the breast: A case report and review of the literature. However, metastasis to the bladder is uncommon. Image showing nuclear atypia with high nuclear…, Positron emission tomography-computed tomography scan…, Positron emission tomography-computed tomography scan fused images for the whole body, showing the…, Image showing intermediate grade ductal carcinoma in situ lacking neuroendocrine features adjacent to…, Differential staining between tumor and adjacent ductal carcinoma in situ with progesterone receptor…, The breast lesion showing the tumor with synaptophysin staining that is positive in…, National Library of Medicine -, Miremadi A, Pinder SE, Lee AH, Bell JA, Paish EC, Wencyk P, et al. Accessibility Epub 2016 Feb 26. Bladder metastasis due to direct infiltration from peripheral organs, such as the colon and rectum, prostate, and cervix, occurs more frequently than metastasis from distant organs, such as the breast. doi: 10.1259/bjr/95130566. Granular cell tumors of the breast: a report of two cases. Reports of breast cancer in young male patients are rare. Case presentation: Here we report a case of metastatic breast cancerto the esophagus with dysphagia as the initial symptom. 2007;80:970–974. Sanguinetti A, Polistena A, Lucchini R, Monacelli M, Galasse S, Avenia S, Bugiantella W, Triola R, Cirocchi R, Rondelli F, Avenia N. Int J Surg Case Rep. 2016;20S(Suppl):5-7. doi: 10.1016/j.ijscr.2016.02.005. Potential of ultra-high-resolution photon-counting CT of bone metastases: initial experiences in breast cancer patients. 2016 Nov;43(12):2022-2025. Background Whereas lymphoma of the female breast is already rare, lymphoma of the male breast has only anecdotally been reported. Our patient underwent a left total mastectomy with sentinel lymph node biopsy and received cisplatin-based adjuvant chemotherapy. Introduction. Yonsei Med J. Case report. A case report of fibroadenoma of the breast with characteristic cystic change on a cut surface Kazuya Miyoshi, Hirotoshi Takahashi, Masaru Inagaki, Jiro Watanabe, Sohsuke Yamada, and Kenichi Mizutani SAGE Open Medical Case Reports 2020 10.1177/2050313X20927612 Since then, only 20 other patients with breast involvement have been documented in the literature till date [ 5 ]. The purpose of this report is to describe a rare case of a metastatic breast carcinoma in the mandibular gingival tissue that mimicked a periodontal abscess. Keywords. More recently, an invasive cancer case was reported in a 30-year-old patient . The multimodality imaging features along with the pathology correlation is presented and the multidisciplinary treatment approach is also reviewed. Primary neuroendocrine small cell carcinoma of the breast. Positron emission tomography-computed tomography imaging excluded any other primary disease. 2020 Apr 29;11:228. doi: 10.3389/fendo.2020.00228. Necrotizing Fasciitis of the Breast: Case Report with Literature Review. s, liver, and brain. 2000 Feb;124(2):296-8. doi: 10.1043/0003-9985(2000)124<0296:PNSCCT>2.0.CO;2. [A Case of Primary Poorly Differentiated/Small Cell Carcinoma of the Breast in a Patient with Von Recklinghausen's Disease]. Case presentation: 8600 Rockville Pike She did not receive adjuvant therapy because there is no consensus on the role of postoperative chemotherapy and radiotherapy. Breast Cancer. Due to the rarity of this entity, prognosis has still not been well established, and treatment has not been standardized, cisplatin-based treatment has been used in this case similar to small cell carcinoma of the lung. A case report. Our patient presented with a fluctuant breast mass diagnosed as a breast abscess. Myoblastoma of the breast: Our experience and review of literature. The purpose of this report is to describe a rare case of a metastatic breast carcinoma in the mandibular gingival tissue that mimicked a periodontal abscess. Conclusions: doi: 10.1259/bjr/97077007. Unable to load your collection due to an error, Unable to load your delegates due to an error. Case presentation A 72-years-old Caucasian man presented with a mass in his left breast. Am J Hematol. The authors declare that they have no competing interests. Hurler syndrome and breast cancer. Granular cell tumour of the breast in a young female: A case report and literature review. A mammogram showed an ill-defined irregular mass in UOQ with no suspicious microcalcification, an ultrasound showed a hypoechoic mass at 9 o’clock 2 × 1.5 cm in size. eCollection 2020. Case report: Second primary small cell carcinoma of the trachea in a breast cancer survivor: a case report and literature review. However, the effectiveness of chemotherapy and radiation is still controversial. The diagnosis of neuroendocrine breast cancer requires the presence of neuroendocrine features in at least 50% of malignant cells, the exclusion of non-mammary primary tumors, as well as the presence of an in situ component in breast histology. This site needs JavaScript to work properly. ALShareef B(1), ALSaleh N(1). FOIA 2013 Jun 5;11:128. doi: 10.1186/1477-7819-11-128. Solid neuroendocrine breast carcinomas: Incidence, clinico-pathological features and immunohistochemical profiling. Conclusion: However, some show malignant transformation, which results in local recurrences or distant metastases. Surgery is the only curable treatment, and removal of AS with adequate surgical margin is important. It accounts for <0.1% of all breast diseases and <2% of all cases of tuberculosis. Breast tuberculosis, also known as tuberculous mastitis, is an extremely rare form of tuberculosis. Neuroendocrine carcinoma of the breast is a well-defined histologic subtype of breast cancer. Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations. 2018 Oct 23;2018:1370680. doi: 10.1155/2018/1370680. A case report of fibroadenoma of the breast with characteristic cystic change on a cut surface Kazuya Miyoshi, Hirotoshi Takahashi, Masaru Inagaki, Jiro Watanabe, Sohsuke Yamada, and Kenichi Mizutani SAGE Open Medical Case Reports 2020 10.1177/2050313X20927612 Surg Oncol. doi: 10.1111/tbj.12121. doi: 10.1016/j.suronc.2009.12.001. Clinical features and treatment response of solid neuroendocrine breast carcinoma to adjuvant chemotherapy and endocrine therapy. Arch Pathol Lab Med 127:1031-1033. Breast lymphoma is a rare entity representing about 0.04–1% of malignant breast neoplasms, less than 1% of non-Hodgkin’s lymphomas and about 1.7% of all extra-nodal lymphomas. Privacy, Help In turn, it may occur as extra-nodal primary disease, primary breast lymphoma or as a result of secondary systemic dissemination [1]. doi: 10.1177/2050313X19841154. Br J Radiol. Granular cell tumor of the breast: correlations between imaging and pathology findings. It is frequently confused with breast carcinoma on clinical and radiological examination, and its diagnosis can therefore be challenging for clinicians, radiologists and pathologists. 8600 Rockville Pike Background: Bethesda, MD 20894, Copyright Introduction. We report the case of a 24-year-old lady presented to our OPD with ulcerated lump in her left breast. She was therefore prescribed several weeks of … We report on a 56-year-old Caucasian female, diagnosed with locally advanced, hormone-receptor-positive, and human epidermal growth factor receptor 2 (HER2)-positive cancer of the left breast. Conclusion: The case described here is the first report of a second occurrence of pregnancy-associated breast cancer. Core biopsy of the breast lesion. This site needs JavaScript to work properly. 2007;35(11):725–727. 2014;2014:408–59. She had no history of breast cancer in her first-degree relative. This case report will augment our understanding of this rare subtype of MBC. -, Pergel A, Yucel AF, Karaca ASA, Aydin I, Ali Sahin D, Demirbag N. A therapeutic and diagnostic dilemma: granular cell tumor of the breast. Introduction Neurofibromatosis type 1 (NF1) is an autosomal dominant neuroectodermal disorder caused by heterozygous loss-of-function mutations of the tumour suppressor gene NF1 on chromosome 17q11.2. This typical clinical case illustrates the different epidemiological, clinical, histological, therapeutic, and evolving aspects of the disease. Al-Balas M, De Leo A, Serra M, Santini D, Taffurelli M. SAGE Open Med Case Rep. 2019 Apr 9;7:2050313X19841154. Please enable it to take advantage of the complete set of features! 2020 Jul 25;37(8):70. doi: 10.1007/s12032-020-01396-4. This case raises the possibility that pregnancy may represent a unique trigger for breast malignancy in a specific cohort of women. Adenomyoepithelioma (AME) of the breast is a very rare tumor and is generally considered to be benign. Breast cancer • Parotid gland • Metastasis. Localization of this lesion to the breast is very rare, accounting for between 5% and 15% of all granular cell tumor cases. An aspirate sample was sent for culture and sensitivities, which revealed the presence of Actinomyces turicensis and the anaerobe Peptoniphilus harei . 1999;6(1):55–58. Pathologists should bear in mind a granular cell tumor when examining material containing cells with abundant granular cytoplasm to avoid misdiagnosing breast carcinoma, which could lead to unnecessary surgery. eCollection 2019. 2019 May;22(5):742-744. doi: 10.4103/njcp.njcp_282_18. We report the case of a 24-year-old lady presented to our OPD with ulcerated lump in her left breast. doi: 10.3349/ymj.2000.41.5.673. Metaplastic carcinomas of the breast are very rare and constitute less than 0.5% of all breast cancers. Less than 25 cases of primary mucinous cystadenocarcinoma of the breast have been reported. Parotid malignant tumors represent 1% to 4% of head and neck cancers, [] of which only 10.4% to 35.6% are secondary lesions.In a majority of cases, the primary lesion is located in the cervico-facial region [].We report a case of parotid metastasis from breast cancer with review of literature. Mammography and ultrasound examination revealed a heterogeneous, irregular and poorly limited mass, located at the union of the outer quadrants of her right breast. -, Wachter DL, Hartmann A, Beckmann MW, Fasching PA, Hein A, Bayer CM, et al. Case presentation: We report the case of a 32-year-old Moroccan woman who presented with a palpable mass in her right breast. Download Citation | On May 21, 2020, Dr. D. Manimala and others published Primary Breast Lymphoma – A Case Report | Find, read and cite all the research you need on ResearchGate Introduction Primary osteosarcoma of the breast is a very rare and aggressive entity, which is histologically indistinguishable from conventional osteosarcoma of the bone and other extraskeletal [ 1 ]. Unable to load your collection due to an error, Unable to load your delegates due to an error, Core biopsy of the breast lesion. Breast cancer; Chemotherapy; Neuroendocrine; Small cell carcinoma. Although ovarian cancer often presents as a widespread disease, metastases to the breast and/or axillary lymph nodes are a very rare event, accounting for only 0.03-0.6% of all breast cancers. We report a case of primary osteosarcoma of the breast occurring in young patient with fatal evolution. Niger J Clin Pract. Irelli A, Sirufo MM, Morelli L, D'Ugo C, Ginaldi L, De Martinis M. J Clin Med. A case report. Our patient remains free of disease to date. Histopathology. JDP 10: 34-37. Our patient presented with a fluctuant breast mass diagnosed as a breast abscess. Careers. We have described the case of a woman with a malignant phyllodes tumor of the breast that was surgically treated. 2020 May 13;9(5):1452. doi: 10.3390/jcm9051452. In April 2013, a 39-year-old female presented to the Department of Surgery, Suining Central Hospital (Suining, China) with a six month history of a painless mass in the left breast. Granular cell tumour of the breast: A rare presentation of a breast mass in an elderly female with a subsequent breast cancer diagnosis. Neuroendocrine Cancer of the Breast: A Rare Entity. Written informed consent was obtained from the patient for publication of this case report and any accompanying images. Our case report describes a patient with a common presenting complaint yet an uncommon infection. Taglietti L, Vettoretto N, Blanzuoli L, Giovanetti M. Updates Surg. Fatnassi R, Bellara I. Granular cell tumor of the breast. Mammography and ultrasound examination revealed a heterogeneous, irregular and poorly limited mass, located at the union of the outer quadrants of her right breast. Image showing nuclear atypia with high nuclear to cytoplasmic ratio, nuclear molding, “salt and pepper” chromatin, and very brisk mitotic rate (hematoxylin and eosin, at high power field), Positron emission tomography-computed tomography scan fused images for the whole body, showing the primary breast lesion and no extra-mammary involvement, Image showing intermediate grade ductal carcinoma, Differential staining between tumor and adjacent ductal carcinoma, The breast lesion showing the tumor with synaptophysin staining that is positive in the tumor in more than 50% of the cells and absent in ductal carcinoma. Bladder metastasis due to direct infiltration from peripheral organs, such as the colon and rectum, prostate, and cervix, occurs more frequently than metastasis from distant organs, such as the breast. Paget's disease of the breast is a rare cancer. Boutrid H, Kassem M, Tozbikian G, Morgan E, White J, Shah M, Vandeusen J, Sardesai S, Williams N, Stover DG, Lustberg M, Wesolowski R, Pudavalli V, Williams TM, Konda B, Fortier S, Carbone D, Ramaswamy B, Cherian MA. Clipboard, Search History, and several other advanced features are temporarily unavailable. Histopathology. An aspirate sample was sent for culture and sensitivities, which revealed the presence of Actinomyces turicensis and the anaerobe Peptoniphilus harei .
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